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Cellosaurus MLEC-Hs6st1-/-;Hs6st2-/- (CVCL_ZD25)

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Cell line name MLEC-Hs6st1-/-;Hs6st2-/-
Synonyms Mouse Lung Endothelial Hs6st1-/-;Hs6st2-/-
Accession CVCL_ZD25
Resource Identification Initiative To cite this cell line use: MLEC-Hs6st1-/-;Hs6st2-/- (RRID:CVCL_ZD25)
Comments Knockout cell: Method=Floxing/Cre recombination; MGI; MGI:1354958; Hs6st1.
Knockout cell: Method=KO mouse; MGI; MGI:1354959; Hs6st2.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Endothelial cell of lung; CL=CL_1001567.
Breed/subspecies: Hs2st1f/f;Hs6st2-/- x C57BL/6J.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_ZD23 (MLEC-Hs6st1f/f;Hs6st2-/-)
Sex of cell Sex unspecified
Age at sampling 8-10W
Category Transformed cell line
Publications

PubMed=30377379; DOI=10.1038/s41592-018-0189-6; PMCID=PMC6214364
Hong Qiu, Song-Shan Shi, Jing-Wen Yue, Meng Xin, Alison V. Nairn, Lei Lin, Xin-Yue Liu, Guo-Yun Li, Stephanie A. Archer-Hartmann, Mitche dela Rosa, Melina Galizzi ...Show all 22 authors... , Shun-Chun Wang, Fu-Ming Zhang, Parastoo Azadi, Toin H. van Kuppevelt, Wellington Veras Cardoso, Koji Kimata, Xing-Bin Ai, Kelley W. Moremen, Jeffrey David Esko, Robert John Linhardt, Lian-Chun Wang; Show fewer authors
A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Nat. Methods 15:889-899(2018)

Cross-references
Cell line collections (Providers) Kerafast; EGA366
Encyclopedic resources Wikidata; Q98127261
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number8