Cellosaurus cell line Mel 04.07 (CVCL

Cross-references
Cell line name	Mel 04.07
Synonyms	04.07
Accession	CVCL_ZD08
Resource Identification Initiative	To cite this cell line use: Mel 04.07 (RRID:CVCL_ZD08)
Comments	From: Leiden University Medical Center; Leiden; Netherlands.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23685455; PubMed=25538140).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=23685455; DOI=10.1038/nature12154 Joanna Kaplon, Liang Zheng, Katrin Meissl, Barbara Chaneton, Vitaly A. Selivanov, Gillian Mackay, Sjoerd H. van der Burg, Elizabeth M.E. Verdegaal, Marta Cascante, Tomer Shlomi, Eyal Gottlieb, Daniel S. Peeper; A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence. Nature 498:109-112(2013) PubMed=25538140; DOI=10.15252/msb.20145450; PMCID=PMC4300494 Marjon A. Smit, Gianluca Maddalo, Kylie Greig, Linsey M. Raaijmakers, Patricia Abrao Possik, Bas van Breukelen, Salvatore Cappadona, Albert J.R. Heck, A.F. Maarten Altelaar, Daniel S. Peeper; ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma. Mol. Syst. Biol. 10:772-772(2014)
Cell line databases/resources	cancercelllines; CVCL_ZD08
Encyclopedic resources	Wikidata; Q98127210
Entry history
Entry creation	02-Jul-2020
Last entry update	14-Aug-2025
Version number	7