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Cellosaurus Mel 12.07 (CVCL_ZD06)

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Cell line name Mel 12.07
Synonyms MEL12.07; 12.07
Accession CVCL_ZD06
Resource Identification Initiative To cite this cell line use: Mel 12.07 (RRID:CVCL_ZD06)
Comments From: Leiden University Medical Center; Leiden; Netherlands.
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Sequence variations
  • Mutation; HGNC; HGNC:1424; CAD; Simple; p.Arg1854Gln (c.5561G>A); ClinVar=VCV001481207; Zygosity=Heterozygous (PubMed=27350335).
  • Mutation; HGNC; HGNC:3330; EML1; Simple; p.Arg64Trp (c.190C>T); Zygosity=Heterozygous (PubMed=27350335).
  • Mutation; HGNC; HGNC:8761; PDCD10; Simple; p.Pro28Ser (c.82C>T); Zygosity=Homozygous (PubMed=27350335).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZD03 ! Mel 04.01
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=27350335; DOI=10.1038/nature18945
Elizabeth M.E. Verdegaal, Noel F.C.C. de Miranda, Marten Visser, Tom Harryvan, Marit M. van Buuren, Rikke Sick Andersen, Sine Reker Hadrup, Caroline E. van der Minne, Remko Schotte, Hergen Spits, John B.A.G. Haanen ...Show all 14 authors... , Ellen H.W. Kapiteijn, Ton Nicolaas Schumacher, Sjoerd H. van der Burg; Show fewer authors
Neoantigen landscape dynamics during human melanoma-T cell interactions.
Nature 536:91-95(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZD06
Encyclopedic resources Wikidata; Q98127216
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number9