Cellosaurus Cre4/2941#6 (CVCL_ZC14)
| Cell line name | Cre4/2941#6 |
|---|---|
| Accession | CVCL_ZC14 |
| Resource Identification Initiative | To cite this cell line use: Cre4/2941#6 (RRID:CVCL_ZC14) |
| Comments | Characteristics: The deletion of Lig3 is accompanied by the loss of mitochondrial DNA. Knockout cell: Method=KO mouse; MGI; MGI:109152; Lig3. Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Embryo; UBERON=UBERON_0000922. Cell type: Fibroblast; CL=CL_0000057. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: B6.Cg-Tg(CAG-cre/Esr1)5Amc/J x Lig3LoxP. |
| Hierarchy | Parent: CVCL_ZB94 (Cre4) |
| Sex of cell | Sex unspecified |
| Age at sampling | 13-14FD |
| Category | Transformed cell line |
| Publications | PubMed=23884459; DOI=10.1074/jbc.M113.472977; PMCID=PMC3772206 |
| Cross-references | |
| Cell line collections (Providers) | Kerafast; ESA110 |
| Encyclopedic resources | Wikidata; Q98125690 |
| Entry history | |
| Entry creation | 02-Jul-2020 |
| Last entry update | 14-Aug-2025 |
| Version number | 9 |