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Cellosaurus AbC1 (CVCL_ZB62)

[Text version]
Cell line name AbC1
Synonyms AbC-1
Accession CVCL_ZB62
Resource Identification Initiative To cite this cell line use: AbC1 (RRID:CVCL_ZB62)
Comments Characteristics: Produces melanin pigment when L-tyrosine or L-DOPA are added to the culture media - along with new organelle formation - melanosomes and increased expression of MSH receptors (Kerafast=EAB001).
Characteristics: Established from the transplantable Bomirski hamster amelanotic melanoma.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Hamster melanoma (NCIt: C133089)
Species of origin Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=6189530; DOI=10.1007/BF01121951
Slominski A.T.
Rapid melanization of Bomirski amelanotic melanoma cells in cell culture.
Biosci. Rep. 3:189-194(1983)

PubMed=2557357; DOI=10.1242/jcs.92.4.551
Slominski A.T., Moellmann G.E., Kuklinska E.
MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis.
J. Cell Sci. 92:551-559(1989)

PubMed=21573540; DOI=10.3892/ijo.2.2.221
Slominski A.T., Paus R.
Bomirski melanomas -- a versatile and powerful model for pigment cell and melanoma research (review).
Int. J. Oncol. 2:221-228(1993)

Cross-references
Cell line collections (Providers) Kerafast; EAB001
Encyclopedic resources Wikidata; Q98125463
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number5