Cellosaurus cell line Pr-111 (CVCL

Cellosaurus Pr-111 (CVCL_Z948)

Cross-references
Cell line name	Pr-111
Synonyms	Pr111
Accession	CVCL_Z948
Resource Identification Initiative	To cite this cell line use: Pr-111 (RRID:CVCL_Z948)
Comments	Doubling time: ~40 hours (PubMed=11896566). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=Under the control of the promoter of rat Psbpc3/Scgb2a2). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Donor information: Established from a mouse suffering from a prostatic intraepithelial neoplasia (PIN) lesion. Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: FVB-Tg(C3-1-TAg)cJeg/JegJ transgenic.
Sex of cell	Male
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=11896566; DOI=10.1038/sj.neo.7900210; PMCID=PMC1550323 Colin R. Soares, Masa-aki Shibata, Jeffrey E. Green, Cheryl Lynn Jorcyk; Development of PIN and prostate adenocarcinoma cell lines: a model system for multistage tumor progression. Neoplasia 4:112-120(2002) PubMed=12235003 Alfonso Calvo, Nian-Qing Xiao, Jason Kang, Carolyn J.M. Best, Isabel Leiva, Michael R. Emmert-Buck, Cheryl Lynn Jorcyk, Jeffrey E. Green; Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors. Cancer Res. 62:5325-5335(2002)
Encyclopedic resources	Wikidata; Q54947811
Entry history
Entry creation	10-Apr-2015
Last entry update	27-Nov-2025
Version number	7