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Cellosaurus COGA-1A (CVCL_Z583)

[Text version]
Cell line name COGA-1A
Synonyms COGA1A; Coga1A
Accession CVCL_Z583
Resource Identification Initiative To cite this cell line use: COGA-1A (RRID:CVCL_Z583)
Comments Microsatellite instability: Instable (MSI) (PubMed=25926053).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Disease Colon carcinoma (NCIt: C4910)
Lynch syndrome (NCIt: C8494)
Lynch syndrome (ORDO: Orphanet_144)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A071 (COGA-1)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): PubMed=25926053

Markers:
AmelogeninX
CSF1PO10,11
D5S81811,12
D7S8207.3,10
D13S3178,11
D16S5399,13
D21S1127,34
TH019,9.3
TPOX9,11
vWA16,18

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Publications

PubMed=18205904; DOI=10.1186/1471-2407-8-13; PMCID=PMC2257953
Brozek W., Bises G., Fabjani G., Cross H.S., Peterlik M.
Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells.
BMC Cancer 8:13.1-13.9(2008)

PubMed=22940288; DOI=10.1016/j.jsbmb.2012.08.003; PMCID=PMC3695570
Hobaus J., Fetahu I.S., Khorchide M., Manhardt T., Kallay E.
Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells.
J. Steroid Biochem. Mol. Biol. 136:296-299(2013)

PubMed=24176760; DOI=10.1016/j.jsbmb.2013.10.015; PMCID=PMC4220008
Fetahu I.S., Hummel D.M., Manhardt T., Aggarwal A., Baumgartner-Parzer S., Kallay E.
Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells.
J. Steroid Biochem. Mol. Biol. 144:228-231(2014)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Anatomy/cell type resources BTO; BTO_0005664
Encyclopedic resources Wikidata; Q54814039
Gene expression databases GEO; GSM1448099
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number13