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Cellosaurus IDE8 (CVCL_Z167)

[Text version]
Cell line name IDE8
Accession CVCL_Z167
Resource Identification Initiative To cite this cell line use: IDE8 (RRID:CVCL_Z167)
Comments Group: Patented cell line.
Group: Tick cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11973.
Omics: Transcriptomics; RNAseq.
Species of origin Ixodes scapularis (Black-legged tick) (Deer tick) (NCBI Taxonomy: 6945)
Sex of cell Mixed sex
Age at sampling Embryo
Category Spontaneously immortalized cell line
Web pages Info; DSMZ; -; https://www.dsmz.de/fileadmin/Bereiche/Microbiology/Dateien/Kultivierungshinweise/TickCellCultureMethods-4.pdf
Info; VectorBase; -; https://vectorbase.org/vectorbase/app/record/dataset/DS_0941d3180e
Provider; TCB; -; https://www.liverpool.ac.uk/research/facilities/tick-cell-biobank/
Publications

PubMed=8057317; DOI=10.1093/jmedent/31.3.425
Chun-Sheng Chen, Ulrike Gertrud Munderloh, Timothy J. Kurtti;
Cytogenetic characteristics of cell lines from Ixodes scapularis (Acari: Ixodidae).
J. Med. Entomol. 31:425-434(1994)

PubMed=8064520; DOI=10.2307/3283188
Ulrike Gertrud Munderloh, Yan Liu, Ma-Ming Wang, Chun-Sheng Chen, Timothy J. Kurtti;
Establishment, maintenance and description of cell lines from the tick Ixodes scapularis.
J. Parasitol. 80:533-543(1994)

PubMed=8812616; DOI=10.1006/jipa.1996.0050
Timothy J. Kurtti, Ulrike Gertrud Munderloh, Theodore George Andreadis, Louis Anthony Magnarelli, Thomas N. Mather;
Tick cell culture isolation of an intracellular prokaryote from the tick Ixodes scapularis.
J. Invertebr. Pathol. 67:318-321(1996)

Patent=US5869335
Ulrike Gertrud Munderloh, Timothy J. Kurtti, Katherine M. Kocan, Edmour F. Blouin, Sidney Alton Ewing;
Propagating bovine parasite by incubation of undifferentiated cells under low oxygen increased carbon dioxide, with organic buffers efficient, large scale production; diagnosis/vaccine for rocky mountains spotted fever.
Patent number US5869335, 09-Feb-1999

PubMed=15053931; DOI=10.1016/j.jcpa.2003.12.002
Lesley Bell-Sakyi;
Ehrlichia ruminantium grows in cell lines from four ixodid tick genera.
J. Comp. Pathol. 130:285-293(2004)

PubMed=17662657; DOI=10.1016/j.pt.2007.07.009
Lesley Bell-Sakyi, Erich Zweygarth, Edmour F. Blouin, Ernest Andrew Gould, Frans Jongejan;
Tick cell lines: tools for tick and tick-borne disease research.
Trends Parasitol. 23:450-457(2007)

PubMed=20388200; DOI=10.1186/1756-3305-3-37; PMCID=PMC2861667
Gertrud Lallinger-Kube, Erich Zweygarth, Lesley Bell-Sakyi, Lygia Maria Friche Passos;
Cold storage and cryopreservation of tick cell lines.
Parasit. Vectors 3:37.1-37.6(2010)

PubMed=22743047; DOI=10.1016/j.ttbdis.2012.05.002; PMCID=PMC3431536
Maria Pilar Alberdi, Matthew John Dalby, Julio Rodriguez-Andres, John K. Fazakerley, Alain Kohl, Lesley Bell-Sakyi;
Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines.
Ticks Tick Borne Dis. 3:137-146(2012)

PubMed=29017825; DOI=10.1016/j.ttbdis.2017.09.014
Mabotse A. Tjale, Alri Pretorius, Antoinette I. Josemans, Mirinda Van Kleef, Junita Liebenberg;
Transcriptomic analysis of Ehrlichia ruminantium during the developmental stages in bovine and tick cell culture.
Ticks Tick Borne Dis. 9:126-134(2018)

PubMed=29886187; DOI=10.1016/j.ttbdis.2018.05.015; PMCID=PMC6052676
Lesley Bell-Sakyi, Alistair C. Darby, Matthew Baylis, Benjamin L. Makepeace;
The Tick Cell Biobank: a global resource for in vitro research on ticks, other arthropods and the pathogens they transmit.
Ticks Tick Borne Dis. 9:1364-1371(2018)

PubMed=32158404; DOI=10.3389/fphys.2020.00152; PMCID=PMC7052283
Ahmed Al-Rofaai, Lesley Bell-Sakyi;
Tick cell lines in research on tick control.
Front. Physiol. 11:152.1-152.7(2020)

Cross-references
Encyclopedic resources Wikidata; Q54897298
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number15