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Cellosaurus Vero E6/NPC1-KO cl.19 (CVCL_YZ66)

[Text version]
Cell line name Vero E6/NPC1-KO cl.19
Synonyms Vero E6/NPC1-KO cl. 19
Accession CVCL_YZ66
Resource Identification Initiative To cite this cell line use: Vero E6/NPC1-KO cl.19 (RRID:CVCL_YZ66)
Comments Group: Non-human primate cell line.
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RYM1; NPC1.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0574 (Vero C1008)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=30010949; DOI=10.1093/infdis/jiy248; PMCID=PMC6927862
Tatsunari Kondoh, Michael Letko, Vincent Jacobus Munster, Rashid Manzoor, Junki Maruyama, Wakako Furuyama, Hiroko Miyamoto, Asako Shigeno, Daisuke Fujikura, Yoshihiro Takadate, Reiko Yoshida ...Show all 15 authors... , Manabu Igarashi, Heinz Feldmann, Andrea Marzi, Ayato Takada; Show fewer authors
Single-nucleotide polymorphisms in human NPC1 influence filovirus entry into cells.
J. Infect. Dis. 218 Suppl. 5:S397-S402(2018)

PubMed=31940478; DOI=10.1016/j.celrep.2019.12.042; PMCID=PMC11075117
Yoshihiro Takadate, Tatsunari Kondoh, Manabu Igarashi, Junki Maruyama, Rashid Manzoor, Hirohito Ogawa, Masahiro Kajihara, Wakako Furuyama, Masahiro Sato, Hiroko Miyamoto, Reiko Yoshida ...Show all 16 authors... , Terence E. Hill, Alexander N. Freiberg, Heinz Feldmann, Andrea Marzi, Ayato Takada; Show fewer authors
Niemann-Pick C1 heterogeneity of bat cells controls filovirus tropism.
Cell Rep. 30:308-319.e5(2020)

Cross-references
Encyclopedic resources Wikidata; Q98134508
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number5