Cellosaurus cell line Vero E6/NPC1-KO cl.19 (CVCL

Cellosaurus Vero E6/NPC1-KO cl.19 (CVCL_YZ66)

Cross-references
Cell line name	Vero E6/NPC1-KO cl.19
Synonyms	Vero E6/NPC1-KO cl. 19
Accession	CVCL_YZ66
Resource Identification Initiative	To cite this cell line use: Vero E6/NPC1-KO cl.19 (RRID:CVCL_YZ66)
Comments	Group: Non-human primate cell line. Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RYM1; NPC1. Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin	Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711)
Hierarchy	Parent: CVCL_0574 (Vero C1008)
Sex of cell	Female
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=30010949; DOI=10.1093/infdis/jiy248; PMCID=PMC6927862 Tatsunari Kondoh, Michael Letko, Vincent Jacobus Munster, Rashid Manzoor, Junki Maruyama, Wakako Furuyama, Hiroko Miyamoto, Asako Shigeno, Daisuke Fujikura, Yoshihiro Takadate, Reiko Yoshida ...Show all 15 authors... , Manabu Igarashi, Heinz Feldmann, Andrea Marzi, Ayato Takada; Show fewer authors Single-nucleotide polymorphisms in human NPC1 influence filovirus entry into cells. J. Infect. Dis. 218 Suppl. 5:S397-S402(2018) PubMed=31940478; DOI=10.1016/j.celrep.2019.12.042; PMCID=PMC11075117 Yoshihiro Takadate, Tatsunari Kondoh, Manabu Igarashi, Junki Maruyama, Rashid Manzoor, Hirohito Ogawa, Masahiro Kajihara, Wakako Furuyama, Masahiro Sato, Hiroko Miyamoto, Reiko Yoshida ...Show all 16 authors... , Terence E. Hill, Alexander N. Freiberg, Heinz Feldmann, Andrea Marzi, Ayato Takada; Show fewer authors Niemann-Pick C1 heterogeneity of bat cells controls filovirus tropism. Cell Rep. 30:308-319.e5(2020)
Encyclopedic resources	Wikidata; Q98134508
Entry history
Entry creation	02-Jul-2020
Last entry update	05-Oct-2023
Version number	5