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Cellosaurus Calu-3 2B4 (CVCL_YZ47)

[Text version]
Cell line name Calu-3 2B4
Synonyms 2B4
Accession CVCL_YZ47
Resource Identification Initiative To cite this cell line use: Calu-3 2B4 (RRID:CVCL_YZ47)
Comments Population: Caucasian.
Characteristics: Increased expression of ACE2.
Virology: Highly susceptible to SARS coronavirus (SARS-CoV) infection (PubMed=20090954).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0609 (Calu-3)
Sex of cell Male
Age at sampling 25Y
Category Cancer cell line

PubMed=20090954; DOI=10.1371/journal.pone.0008729
Yoshikawa T., Hill T.E., Yoshikawa N., Popov V.L., Galindo C.L., Garner H.R., Peters C.J., Tseng C.-T.
Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.
PLoS ONE 5:E8729-E8729(2010)

Cell line databases/resources cancercelllines; CVCL_YZ47
Encyclopedic resources Wikidata; Q98125608
Gene expression databases GEO; GSE17400
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number7