Cellosaurus cell line FHS042i-sh22512D (CVCL

Cellosaurus FHS042i-sh22512D (CVCL_YY73)

Cross-references
Cell line name	FHS042i-sh22512D
Synonyms	iPSC - 22512D
Accession	CVCL_YY73
Resource Identification Initiative	To cite this cell line use: FHS042i-sh22512D (RRID:CVCL_YY73)
Comments	Part of: Framingham Heart Study (FHS) collection. Part of: Next Generation Genetic Association studies (Next Gen) program cell lines. Population: Caucasian. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:3231; CELSR2; Simple; c.*919G>T; dbSNP=rs12740374; Zygosity=Homozygous; Note=Minor haplotype (PubMed=28388431).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_YY72 ! FHS041i-sh22512A
Sex of cell	Female
Age at sampling	71-80Y
Category	Induced pluripotent stem cell
Publications	PubMed=28388431; DOI=10.1016/j.stem.2017.01.010 Curtis R. Warren, John F. O'Sullivan, Max Friesen, Caroline E. Becker, Xiao-Ling Zhang, Po-Ching Liu, Yoshiyuki Wakabayashi, Jordan E. Morningstar, Xu Shi, Jihoon Choi, Fang Xia ...Show all 28 authors... , Derek Tilghman Peters, Mary Heather Celine Florido, Alexander M. Tsankov, Eilene A. Duberow, Lauren Comisar, Jennifer Shay, Xin Jiang, Alexander Meissner, Kiran Musunuru, Sekar Kathiresan, Laurence Daheron, Jun Zhu, Robert Edgardo Gerszten, Rahul C. Deo, Ramachandran S. Vasan, Christopher J. O'Donnell, Chad A. Cowan; Show fewer authors Induced pluripotent stem cell differentiation enables functional validation of GWAS variants in metabolic disease. Cell Stem Cell 20:547-557.e7(2017)
Cell line collections (Providers)	WiCell; fhs042i-sh22512d
Biological sample resources	BioSample; SAMN06093726
Encyclopedic resources	Wikidata; Q98126174
Gene expression databases	GEO; GSM2411820
Entry history
Entry creation	02-Jul-2020
Last entry update	10-Apr-2025
Version number	9