Cellosaurus cell line FHS014i-sh1296E (CVCL

Cellosaurus FHS014i-sh1296E (CVCL_YY45)

Cross-references
Cell line name	FHS014i-sh1296E
Synonyms	iPSC - 1296E
Accession	CVCL_YY45
Resource Identification Initiative	To cite this cell line use: FHS014i-sh1296E (RRID:CVCL_YY45)
Comments	Part of: Framingham Heart Study (FHS) collection. Part of: Next Generation Genetic Association studies (Next Gen) program cell lines. Population: Caucasian. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:3231; CELSR2; Simple; c.*919G>T (chr1:g.109274968G>T); ClinVar=VCV000007081; Zygosity=Homozygous; Note=Minor haplotype (PubMed=28388431).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_YY44 ! FHS013i-sh1296C
Sex of cell	Female
Age at sampling	71-80Y
Category	Induced pluripotent stem cell
Publications	PubMed=28388431; DOI=10.1016/j.stem.2017.01.010 Curtis R. Warren, John F. O'Sullivan, Max Friesen, Caroline E. Becker, Xiao-Ling Zhang, Po-Ching Liu, Yoshiyuki Wakabayashi, Jordan E. Morningstar, Xu Shi, Jihoon Choi, Fang Xia ...Show all 28 authors... , Derek Tilghman Peters, Mary Heather Celine Florido, Alexander M. Tsankov, Eilene A. Duberow, Lauren Comisar, Jennifer Shay, Xin Jiang, Alexander Meissner, Kiran Musunuru, Sekar Kathiresan, Laurence Daheron, Jun Zhu, Robert Edgardo Gerszten, Rahul C. Deo, Ramachandran S. Vasan, Christopher J. O'Donnell, Chad A. Cowan; Show fewer authors Induced pluripotent stem cell differentiation enables functional validation of GWAS variants in metabolic disease. Cell Stem Cell 20:547-557.e7(2017)
Cell line collections (Providers)	WiCell; fhs014i-sh1296e
Biological sample resources	BioSample; SAMN06093740
Encyclopedic resources	Wikidata; Q98126056
Gene expression databases	GEO; GSM2411806
Entry history
Entry creation	02-Jul-2020
Last entry update	27-Nov-2025
Version number	10