Cellosaurus cell line FHS012i-sh1293B (CVCL

Cellosaurus FHS012i-sh1293B (CVCL_YY43)

Cross-references
Cell line name	FHS012i-sh1293B
Synonyms	iPSC - 1293B
Accession	CVCL_YY43
Resource Identification Initiative	To cite this cell line use: FHS012i-sh1293B (RRID:CVCL_YY43)
Comments	Part of: Framingham Heart Study (FHS) collection. Part of: Next Generation Genetic Association studies (Next Gen) program cell lines. Population: Caucasian. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:3231; CELSR2; Simple; c.*919G>T (chr1:g.109274968G>T); ClinVar=VCV000007081; Zygosity=Homozygous; Note=Minor haplotype (PubMed=28388431).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_YY42 ! FHS011i-sh1293A
Sex of cell	Male
Age at sampling	81-90Y
Category	Induced pluripotent stem cell
Publications	PubMed=28388431; DOI=10.1016/j.stem.2017.01.010 Curtis R. Warren, John F. O'Sullivan, Max Friesen, Caroline E. Becker, Xiao-Ling Zhang, Po-Ching Liu, Yoshiyuki Wakabayashi, Jordan E. Morningstar, Xu Shi, Jihoon Choi, Fang Xia ...Show all 28 authors... , Derek Tilghman Peters, Mary Heather Celine Florido, Alexander M. Tsankov, Eilene A. Duberow, Lauren Comisar, Jennifer Shay, Xin Jiang, Alexander Meissner, Kiran Musunuru, Sekar Kathiresan, Laurence Daheron, Jun Zhu, Robert Edgardo Gerszten, Rahul C. Deo, Ramachandran S. Vasan, Christopher J. O'Donnell, Chad A. Cowan; Show fewer authors Induced pluripotent stem cell differentiation enables functional validation of GWAS variants in metabolic disease. Cell Stem Cell 20:547-557.e7(2017)
Cell line collections (Providers)	WiCell; fhs012i-sh1293b
Biological sample resources	BioSample; SAMN06093692
Encyclopedic resources	Wikidata; Q98126050
Gene expression databases	GEO; GSM2411766
Entry history
Entry creation	02-Jul-2020
Last entry update	27-Nov-2025
Version number	10