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Cellosaurus NCC-MPNST2-C1 (CVCL_YU13)

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Cell line name NCC-MPNST2-C1
Synonyms NCCMPNST2C1
Accession CVCL_YU13
Resource Identification Initiative To cite this cell line use: NCC-MPNST2-C1 (RRID:CVCL_YU13)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 49 hours (PubMed=32099531).
Omics: Phenotyping; Drug screening.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Leu179Tyrfs*11 (c.536_539del); Zygosity=Unspecified (PubMed=32099531).
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=32099531

Markers:
AmelogeninX
CSF1PO10,12
D5S81811
D7S8208
D13S31710
D16S5399,11
D21S1131.2
TH019
TPOX11
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=32099531; DOI=10.1186/s12935-020-1128-z; PMCID=PMC7031935
Rieko Oyama, Fusako Kito, Mami Takahashi, Emi Hattori, Rei Noguchi, Yoko Takai, Marimu Sakumoto, Zhi-Wei Qiao, Shunichi Toki, Masato Sugawara, Yoshikazu Tanzawa ...Show all 17 authors... , Eisuke Kobayashi, Fumihiko Nakatani, Shintaro Iwata, Akihiko Yoshida, Akira Kawai, Tadashi Kondo; Show fewer authors
Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors.
Cancer Cell Int. 20:58.1-58.15(2020)

Cross-references
Cell line databases/resources DepMap; ACH-002800
Encyclopedic resources Wikidata; Q95992535
Entry history
Entry creation12-Mar-2020
Last entry update27-Nov-2025
Version number11