Cellosaurus cell line SK-OV-3-hCD271 (CVCL

Cellosaurus SK-OV-3-hCD271 (CVCL_YU10)

Cross-references
Cell line name	SK-OV-3-hCD271
Synonyms	SK-OV-3-CD271
Accession	CVCL_YU10
Resource Identification Initiative	To cite this cell line use: SK-OV-3-hCD271 (RRID:CVCL_YU10)
Comments	Population: Caucasian. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7809; NGFR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease	Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0532 (SK-OV-3)
Sex of cell	Female
Age at sampling	64Y
Category	Cancer cell line
Publications	PubMed=32069133; DOI=10.1089/mab.2019.0040 Shinkichi Morita, Mai Mochizuki, Rie Shibuya-Takahashi, Mao Nakamura-Shima, Tomoko Yamazaki, Takayuki Imai, Yukinori Asada, Kazuto Matsuura, Sadafumi Kawamura, Kazunori Yamaguchi, Jun Yasuda ...Show all 15 authors... , Kazuo Sugamura, Yukio Katori, Kennichi Satoh, Keiichi Tamai; Show fewer authors Establishment of a monoclonal antibody that recognizes cysteine-rich domain 1 of human CD271. Monoclon. Antib. Immunodiagn. Immunother. 39:6-11(2020)
Cell line databases/resources	cancercelllines; CVCL_YU10
Encyclopedic resources	Wikidata; Q98132669
Entry history
Entry creation	12-Mar-2020
Last entry update	14-Aug-2025
Version number	11