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Cellosaurus Hep-G2/C3A-hARG1 (CVCL_YN88)

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Cell line name Hep-G2/C3A-hARG1
Synonyms C3_A
Accession CVCL_YN88
Resource Identification Initiative To cite this cell line use: Hep-G2/C3A-hARG1 (RRID:CVCL_YN88)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:663; ARG1.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1098 (Hep-G2/C3A)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

DOI=10.1016/j.bbe.2019.12.006
Krzysztof Dariusz Pluta, Anna Samluk, Agnieszka Wencel, Karolina Ewa Zakrzewska, Monika Gora, Beata Burzynska, Malgorzata Ciezkowska, Joanna Motyl, Dorota Genowefa Pijanowska;
Genetically modified C3A cells with restored urea cycle for improved bioartificial liver.
Biocybern. Biomed. Eng. 40:378-387(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_YN88
Encyclopedic resources Wikidata; Q94102457
Entry history
Entry creation12-Mar-2020
Last entry update19-Dec-2024
Version number10