Cellosaurus cell line UWG02CTC (CVCL

Cellosaurus UWG02CTC (CVCL_YN87)

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Cell line name

UWG02CTC

Synonyms

University of Wollongong Gastric cancer 02 Circulating Tumor Cells

Accession

CVCL_YN87

Resource Identification Initiative

To cite this cell line use: UWG02CTC (RRID:CVCL_YN87)

Comments

Doubling time: 18 hours (Direct_author_submission).
Miscellaneous: Age of donor, doubling time and zygosity of sequence variations from personal communication of Brungs, Daniel.
Derived from site: Metastatic; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Mutation; HGNC; HGNC:2348; CREBBP; Simple; p.Arg1446Cys (c.4336C>T); ClinVar=VCV000095047; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser33Phe (c.98C>T); ClinVar=VCV000017583; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:4392; GNAS; Simple; p.Arg201His (c.602G>A); ClinVar=VCV000015934; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:7029; MET; Simple; p.Thr992Ile (c.2975C>T) (p.Thr1010Ile, c.3029C>T); ClinVar=VCV000041624; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu418Lys (c.1252G>A); ClinVar=VCV000045464; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Gln (c.1624G>C); ClinVar=VCV000376244; Zygosity=Heterozygous (PubMed=31953491).
Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Asp537His (c.1609G>C); Zygosity=Homozygous (PubMed=31953491).

Disease

Gastric adenocarcinoma (NCIt: C4004)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_YN86 ! UWG02ASC

Sex of cell

Male

Age at sampling

61Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31953491

Markers:

Amelogenin	X,Y
CSF1PO	10,12
D2S1338	19
D3S1358	15,16
D5S818	12
D7S820	11,12
D8S1179	11,13
D13S317	12
D16S539	11
D18S51	14
D19S433	13,15
D21S11	30,31
FGA	22,23
Penta D	9,14
Penta E	7
TH01	6,7
TPOX	8
vWA	16

Publications

PubMed=31953491; DOI=10.1038/s41598-019-57164-6; PMCID=PMC6968999
Daniel Brungs, Elahe Minaei, Ann-Katrin Piper, Jay R. Perry, Ashleigh Splitt, Martin G. Carolan, Shantay Ryan, Xiao Juan Wu, Stephanie Corde, Moeava Tehei, Morteza Aghmesheh ...Show all 14 authors... , Kara Lea Vine, Therese M. Becker, Marie Ranson; Show fewer authors
Establishment of novel long-term cultures from EpCAM positive and negative circulating tumour cells from patients with metastatic gastroesophageal cancer.
Sci. Rep. 10:539.1-539.13(2020)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_YN87

Encyclopedic resources

Wikidata; Q98134460

Entry history

Entry creation

12-Mar-2020

Last entry update

19-Dec-2024

Version number