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Cellosaurus UBi001-A-3 (CVCL_YN11)

[Text version]
Cell line name UBi001-A-3
Synonyms NAGLU3; NAGLU-3
Accession CVCL_YN11
Resource Identification Initiative To cite this cell line use: UBi001-A-3 (RRID:CVCL_YN11)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Universidad Autonoma de Barcelona; Barcelona; Spain.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:7632; NAGLU; Simple_edited; p.Phe288_Ile290del; Zygosity=Homozygous; Note=By CRISPR/Cas9 (PubMed=31825816).
Disease Mucopolysaccharidosis type IIIB (NCIt: C84898)
Sanfilippo syndrome type B (ORDO: Orphanet_79270)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_YM94 (UBi001-A)
Sex of cell Male
Age at sampling Age unspecified
Category Induced pluripotent stem cell
STR profile Source(s): BNLC

Markers:
AmelogeninX,Y
CSF1PO10,13
D5S81812
D7S82010,13
D13S31712
D16S53911,13
D21S1129
TH018,9
TPOX9,11
vWA17

Run an STR similarity search on this cell line
Web pages Provider; BNLC; -; https://www.isciii.es/documents/20119/880364/Caracteristicas+-+NAGLU3+Solicitud+de+dep%C3%B3sito-v3.pdf
Provider; BNLC; -; https://www.isciii.es/documents/20119/880377/NAGLU3%2520Anexo.pdf
Publications

PubMed=31825816; DOI=10.1016/j.scr.2019.101668
Beneto N., Cozar M., Gort L., Pacheco L., Vilageliu L., Grinberg D., Canals I.
Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome.
Stem Cell Res. 42:101668-101668(2020)

Cross-references
Cell line databases/resources hPSCreg; UBi001-A-3
Encyclopedic resources Wikidata; Q98133810
Entry history
Entry creation12-Mar-2020
Last entry update10-Apr-2025
Version number10