Cellosaurus cell line 6499c3 (CVCL

Cellosaurus 6499c3 (CVCL_YM25)

Cross-references
Cell line name	6499c3
Accession	CVCL_YM25
Resource Identification Initiative	To cite this cell line use: 6499c3 (RRID:CVCL_YM25)
Comments	Genetic integration: Method=Transgenic mouse; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp). Omics: Transcriptomics; RNAseq. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264. Breed/subspecies: KrasLSL-G12D/+;Trp53LSL-R172H/+;Pdx1-Cre;Rosa26YFP/YFP (KPCY).
Disease	Mouse pancreatic neoplasm (NCIt: C34035)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Originate from same individual	CVCL_YM26 ! 6499c4
Category	Cancer cell line
Publications	PubMed=29958801; DOI=10.1016/j.immuni.2018.06.006; PMCID=PMC6707727 Jin-Yang Li, Katelyn T. Byrne, Fang-Xue Yan, Taiji Yamazoe, Ze-Yu Chen, Timour Baslan, Lee P. Richman, Jeffrey H. Lin, Yu H. Sun, Andrew J. Rech, David Balli ...Show all 29 authors... , Ceire A. Hay, Yogev Sela, Allyson J. Merrell, Shannon M. Liudahl, Naomi Gordon, Robert J. Norgard, Salina Yuan, Si-Xiang Yu, Timothy Chao, Shuai Ye, Tzipora Sarah Karin Eisinger-Mathason, Robert Babak Faryabi, John W. Tobias, Scott William Lowe, Lisa M. Coussens, Edward John Wherry 3rd, Robert Herman Vonderheide, Ben Z. Stanger; Show fewer authors Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy. Immunity 49:178-193.e7(2018)
Cell line collections (Providers)	Kerafast; EUP007-FP
Encyclopedic resources	Wikidata; Q93308896
Gene expression databases	GEO; GSM2974126 GEO; GSM2974164 GEO; GSM2974212 GEO; GSM2974920 GEO; GSM2974921
Entry history
Entry creation	12-Mar-2020
Last entry update	10-Apr-2025
Version number	6