Cellosaurus U2OS MPX-Nomad NK2R (CVCL_YK71)
Cell line name | U2OS MPX-Nomad NK2R |
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Synonyms | MPXNomad NK2R; MultiPleXed-Nomad NK2R U2OS |
Accession | CVCL_YK71 |
Resource Identification Initiative | To cite this cell line use: U2OS MPX-Nomad NK2R (RRID:CVCL_YK71) |
Comments | Population: Caucasian. Characteristics: The green calcium-Nomad biosensor consists of a membrane localization peptide derived from interleukin-2 receptor alpha chain, a TurboGFP fluorescent protein, a calmodulin-binding peptide fused to a KDEL signal. Characteristics: The red cAMP-Nomad biosensor consists of a membrane localization peptide derived from interleukin-2 receptor alpha chain, a TurboFP650 fluorescent protein, a Ht31 peptide fused to a KDEL signal. Transfected with: HGNC; 11527; TACR2. Transfected with: UniProtKB; J9PBR7; Entacmaea quadricolor far-red fluorescent protein eqFP650. Transfected with: UniProtKB; Q6WV12; Pontellina plumata GFP2 (with p.Lys5Glu, p.Val117Met, p.Val149Asp, p.Val151Asp, p.Ala155Thr, p.Phe168Ser and p.Leu200Asp = TurboGFP). Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979. |
Sequence variations |
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Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_YK69 (U2OS MPX-Nomad) |
Sex of cell | Female |
Age at sampling | 15Y |
Category | Cancer cell line |
Publications | PubMed=29412765; DOI=10.1177/2472630318754828 |
Cross-references | |
Encyclopedic resources | Wikidata; Q98133759 |
Entry history | |
Entry creation | 19-Dec-2019 |
Last entry update | 05-Oct-2023 |
Version number | 9 |