Cellosaurus U2OS ADCYAP1R1 cAMP-Nomad (CVCL_YK25)
| Cell line name | U2OS ADCYAP1R1 cAMP-Nomad |
|---|---|
| Synonyms | PAC1R cAMPNomad; PAC1R Nomad; cAMP Nomad PAC1R; cAMPNomad-PACAPR |
| Accession | CVCL_YK25 |
| Resource Identification Initiative | To cite this cell line use: U2OS ADCYAP1R1 cAMP-Nomad (RRID:CVCL_YK25) |
| Comments | Population: Caucasian. Characteristics: In absence of cAMP, the fluorescent biosensor is localized in the cellular membrane. An increase in this second messenger concentration leads to change in the structural folding of Nomad biosensor that promotes its cellular relocation in the vesicular trafficking of the cells. Characteristics: The red cAMP-Nomad biosensor consists of a membrane localization peptide derived from interleukin-2 receptor alpha chain, a TurboFP650 fluorescent protein, a Ht31 peptide fused to a KDEL signal. Transfected with: HGNC; 242; ADCYAP1R1. Transfected with: UniProtKB; J9PBR7; Entacmaea quadricolor far-red fluorescent protein eqFP650. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979. |
| Sequence variations |
|
| Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0042 (U2OS) |
| Sex of cell | Female |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | Innoprot; P70513 |
| Encyclopedic resources | Wikidata; Q98133720 |
| Entry history | |
| Entry creation | 19-Dec-2019 |
| Last entry update | 05-Oct-2023 |
| Version number | 9 |