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Cellosaurus MCF10A-KRAS (CVCL_YI68)

[Text version]
Cell line name MCF10A-KRAS
Accession CVCL_YI68
Resource Identification Initiative To cite this cell line use: MCF10A-KRAS (RRID:CVCL_YI68)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6407; KRAS (Note=With p.Gly12Val (c.35G>T)).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=31467290

Markers:
AmelogeninX
CSF1PO10,12
D2S133821,26
D3S135814,18
D5S81810,13
D7S82010,11
D8S117914,16
D13S3178,9
D16S53910,12
D18S5118,19
D19S43313,15
D21S1128,30
FGA22,24
TH018,9.3
TPOX9,11
vWA15,17

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Publications

PubMed=31467290; DOI=10.1038/s41597-019-0166-7; PMCID=PMC6715692
Regine M. Schoenherr, Dong-Qing Huang, Uliana J. Voytovich, Richard G. Ivey, Jacob J. Kennedy, Richard G. Saul, Simona Colantonio, Rhonda R. Roberts, Joseph G. Knotts, Jan A. Kaczmarczyk, Candice Perry ...Show all 19 authors... , Stephen M. Hewitt, William Bocik, Gordon R. Whiteley, Tara Hiltke, Emily S. Boja, Henry Rodriguez, Jeffrey R. Whiteaker, Amanda Grace Paulovich; Show fewer authors
A dataset describing a suite of novel antibody reagents for the RAS signaling network.
Sci. Data 6:160.1-160.11(2019)

Cross-references
Encyclopedic resources Wikidata; Q95986682
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number10