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Cellosaurus HEK293 RPS2 WT (CVCL_YD70)

[Text version]
Cell line name HEK293 RPS2 WT
Accession CVCL_YD70
Resource Identification Initiative To cite this cell line use: HEK293 RPS2 WT (RRID:CVCL_YD70)
Comments Characteristics: Transfected with wild type Rps2 linked to IRES-eGFP.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:105110; Rps2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Omics: Metabolomics.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=31637312; DOI=10.1038/s42003-019-0626-9; PMCID=PMC6797716
Dmitri Shcherbakov, Youjin Teo, Heithem Boukari, Adrian Cortes-Sanchon, Matilde Mantovani, Ivan Osinnii, James Moore, Reda Juskeviciene, Margarita Brilkova, Stefan Duscha, Harshitha Santhosh Kumar ...Show all 16 authors... , Endre Laczko, Hubert Rehrauer, Eric Westhof, Rashid Akbergenov, Erik Christian Bottger; Show fewer authors
Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis.
Commun. Biol. 2:381.1-381.16(2019)

Cross-references
Encyclopedic resources Wikidata; Q94094921
Gene expression databases GEO; GSM3168269
GEO; GSM3168270
GEO; GSM3168271
GEO; GSM3168272
Metabolomic databases MetaboLights; MTBLS106
Entry history
Entry creation19-Dec-2019
Last entry update14-Aug-2025
Version number10