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Cellosaurus hSABCi-NS1.1 (CVCL_YB44)

[Text version]
Cell line name hSABCi-NS1.1
Synonyms human Small Airway Basal Cells immortalized-NonSmoker 1.1
Accession CVCL_YB44
Resource Identification Initiative To cite this cell line use: hSABCi-NS1.1 (RRID:CVCL_YB44)
Comments Population: African American.
Characteristics: Useful for understanding the biology of small airway epithelium (SAE), the pathogenesis of SAE-related diseases and testing new pharmacologic agents (PubMed=31443657).
Doubling time: 16 hours (PubMed=31443657).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Airway epithelium basal cell; CL=CL_0002633.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 50Y
Category Telomerase immortalized cell line
Publications

PubMed=31443657; DOI=10.1186/s12931-019-1140-9; PMCID=PMC6708250
Guo-Qing Wang, Howard H. Lou, Jacqueline Salit, Philip L. Leopold, Sharon Driscoll, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal;
Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Respir. Res. 20:196.1-196.14(2019)

Cross-references
Encyclopedic resources Wikidata; Q94301994
Gene expression databases GEO; GSE124265
Entry history
Entry creation19-Dec-2019
Last entry update14-Aug-2025
Version number12