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Cellosaurus BFTC-909 pBabeAR1 (CVCL_YB38)

[Text version]
Cell line name BFTC-909 pBabeAR1
Synonyms BFTC 909 pBabeAR1
Accession CVCL_YB38
Resource Identification Initiative To cite this cell line use: BFTC-909 pBabeAR1 (RRID:CVCL_YB38)
Comments Population: Chinese; Taiwan.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:644; AR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Kidney, renal pelvis; UBERON=UBERON_0001224.
Sequence variations
  • Gene fusion; HGNC; HGNC:2151; CNGB1 + HGNC; HGNC:6326; KIFC3; Name(s)=KIFC3-CNGB1 (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Cys (c.722C>G); ClinVar=VCV000177791; Zygosity=Heterozygous (from parent cell line).
Disease Renal pelvis urothelial carcinoma (NCIt: C7355)
Upper tract urothelial carcinoma (ORDO: Orphanet_598216)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1084 (BFTC-909)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=23599788; DOI=10.3892/ol.2013.1140; PMCID=PMC3629091
Teng-Fu Hsieh, Chi-Cheng Chen, Ai-Lin Yu, Wen-Lung Ma, Cai-Xia Zhang, Chih-Rong Shyr, Chawn-Shang Chang;
Androgen receptor decreases the cytotoxic effects of chemotherapeutic drugs in upper urinary tract urothelial carcinoma cells.
Oncol. Lett. 5:1325-1330(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_YB38
Encyclopedic resources Wikidata; Q93425847
Entry history
Entry creation19-Dec-2019
Last entry update14-Aug-2025
Version number13