• Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ile2675Aspfs*6 (c.8021dupA) (c.8021_8022insA); ClinVar=VCV000267050; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg24Serfs*20 (c.68dupG) (c.68_69insG) (p.G23fs); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:3373; EP300; Simple; p.Met1470Cysfs*22 (c.4408delA); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:3373; EP300; Simple; p.Asn1700Thrfs*9 (c.5099delA); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Leu450Ter (c.1349delT) (p.Leu450fs) (c.1344delT); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11986; TOP1; Simple; p.Arg621His (c.1862G>A); Zygosity=Heterozygous (PubMed=21619602).
  
• Mutation; HGNC; HGNC:11986; TOP1; Simple; p.Glu710Gly (c.2129A>G); Zygosity=Heterozygous (PubMed=21619602).
  

PubMed=15027118; DOI=10.1002/ijc.20032
Laurent Candeil, Isabelle Gourdier, Delphine Peyron, Nadia Vezzio-Vie, Virginie Copois, Frederic Bibeau, Beatrice Orsetti, George L. Scheffer, Marc Ychou, Qasim A. Khan, Yves Pommier ...Show all 14 authors... , Bernard Pau, Pierre Martineau, Maguy Del Rio; Show fewer authors
ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.
Int. J. Cancer 109:848-854(2004)

PubMed=18340113; DOI=10.4161/cbt.7.6.5838
Celine Gongora, Laurent Candeil, Nadia Vezzio-Vie, Virginie Copois, Vincent Denis, Corinne Bareil, Franck Molina, Caroline Fraslon, Emmanuel Conseiller, Bernard Pau, Pierre Martineau, Maguy Del Rio;
Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.
Cancer Biol. Ther. 7:822-832(2008)

PubMed=21619602; DOI=10.1186/1476-4598-10-64; PMCID=PMC3120799
Celine Gongora, Nadia Vezzio-Vie, Sandie Tuduri, Vincent Denis, Annick Causse, Celine Auzanneau, Gwenaelle Collod-Beroud, Arnaud Coquelle, Philippe Pasero, Phillipe Pourquier, Pierre Martineau, Maguy Del Rio;
New topoisomerase I mutations are associated with resistance to camptothecin.
Mol. Cancer 10:64.1-64.13(2011)