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Cellosaurus PGA-1 (CVCL_Y545)

[Text version]
Cell line name PGA-1
Synonyms PGA1; PG A1; CLL-PGA
Accession CVCL_Y545
Resource Identification Initiative To cite this cell line use: PGA-1 (RRID:CVCL_Y545)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: LL-100 blood cancer cell line panel.
Population: Caucasian.
Doubling time: ~50 hours (DSMZ=ACC-766).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
HLA typing Source: DSMZCellDive=ACC-766
Class I
HLA-AA*02:01:01,03:01:01
HLA-BB*35:03:01,39:01:01
HLA-CC*07:02:01,12:03:01
Class II
HLA-DPDPA1*01:03:01,01:03:01
DPB1*04:02:01,02:01:02
HLA-DQDQA1*01:02:01,05:05:01
DQB1*03:01:01,06:09:01
HLA-DRDRA*01:02:02,01:02:02
DRB1*12:01:01,13:02:01
Disease Chronic lymphocytic leukemia (NCIt: C3163)
B-cell chronic lymphocytic leukemia (ORDO: Orphanet_67038)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_Y555 ! PG/B95-8
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001634; DSMZ=ACC-766

Markers:
AmelogeninX,Y
CSF1PO13
D2S133817,18
D3S135815,16
D5S81811,12
D7S82010,11
D8S117913
D13S3178,12
D16S53912
D18S5115
D19S43314,15
D21S1128,30
FGA20,22
Penta D9,14
Penta E12
TH016,9.3
TPOX8,11
vWA17

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Publications

PubMed=2836321; DOI=10.1002/ijc.2910410621
Nongnit Lewin, Pierre Aman, Hakan Mellstedt, Lore Zech, George Klein;
Direct outgrowth of in vivo Epstein-Barr virus (EBV)-infected chronic lymphocytic leukemia (CLL) cells into permanent lines.
Int. J. Cancer 41:892-895(1988)

PubMed=23297799; DOI=10.3109/10428194.2013.764418
Anna Lanemo Myhrinder, Eva Hellqvist, Ann-Charlotte Bergh, Mattias Jansson, Kenneth Nilsson, Per Hultman, Jon Jonasson, Anne Mette Buhl, Lone Bredo Pedersen, Jesper Jurlander, Eva Klein ...Show all 15 authors... , Nicole Weit, Marco Herling, Richard Rosenquist, Anders Rosen; Show fewer authors
Molecular characterization of neoplastic and normal 'sister' lymphoblastoid B-cell lines from chronic lymphocytic leukemia.
Leuk. Lymphoma 54:1769-1779(2013)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Hilmar Quentmeier, Claudia Pommerenke, Wilhelm Gerhard Dirks, Sonja Eberth, Max Koeppel, Roderick A.F. MacLeod, Stefan Nagel, Klaus G. Steube, Cord C. Uphoff, Hans Gunther Drexler;
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218.1-8218.14(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-766
NCBI_Iran; C583
Cell line databases/resources cancercelllines; CVCL_Y545
Cell_Model_Passport; SIDM01855
DepMap; ACH-001634
DSMZCellDive; ACC-766
Encyclopedic resources Wikidata; Q54947324
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Entry history
Entry creation07-Nov-2014
Last entry update10-Apr-2025
Version number15