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Cellosaurus WD39 (CVCL_Y528)

[Text version]
Cell line name WD39
Accession CVCL_Y528
Resource Identification Initiative To cite this cell line use: WD39 (RRID:CVCL_Y528)
Comments Population: Japanese.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 16Y
Category Induced pluripotent stem cell
Publications

PubMed=23039195; DOI=10.1186/1756-6606-5-35; PMCID=PMC3546866
Imaizumi Y., Okada Y., Akamatsu W., Koike M., Kuzumaki N., Hayakawa H., Nihira T., Kobayashi T., Ohyama M., Sato S., Takanashi M., Funayama M., Hirayama A., Soga T., Hishiki T., Suematsu M., Yagi T., Ito D., Kosakai A., Hayashi K., Shouji M., Nakanishi A., Suzuki N., Mizuno Y., Mizushima N., Amagai M., Uchiyama Y., Mochizuki H., Hattori N., Okano H.
Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Mol. Brain 5:35.1-35.13(2012)

PubMed=24389010; DOI=10.1016/j.neuron.2013.10.053
Bundo M., Toyoshima M., Okada Y., Akamatsu W., Ueda J., Nemoto-Miyauchi T., Sunaga F., Toritsuka M., Ikawa D., Kakita A., Kato M., Kasai K., Kishimoto T., Nawa H., Okano H., Yoshikawa T., Kato T., Iwamoto K.
Increased L1 retrotransposition in the neuronal genome in schizophrenia.
Neuron 81:306-313(2014)

PubMed=24936452; DOI=10.1016/j.stemcr.2014.03.007; PMCID=PMC4050482
Numasawa-Kuroiwa Y., Okada Y., Shibata S., Kishi N., Akamatsu W., Shoji M., Nakanishi A., Oyama M., Osaka H., Inoue K., Takahashi K., Yamanaka S., Kosaki K., Takahashi T., Okano H.
Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes.
Stem Cell Reports 2:648-661(2014)

PubMed=26056228; DOI=10.1093/hmg/ddv212
Ohta E., Nihira T., Uchino A., Imaizumi Y., Okada Y., Akamatsu W., Takahashi K., Hayakawa H., Nagai M., Ohyama M., Ryo M., Ogino M., Murayama S., Takashima A., Nishiyama K., Mizuno Y., Mochizuki H., Obata F., Okano H.
I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3beta signaling pathway.
Hum. Mol. Genet. 24:4879-4900(2015)

PubMed=28052261; DOI=10.1016/j.celrep.2016.12.020
Hosoya M., Fujioka M., Sone T., Okamoto S., Akamatsu W., Ukai H., Ueda H.R., Ogawa K., Matsunaga T., Okano H.
Cochlear cell modeling using disease-specific iPSCs unveils a degenerative phenotype and suggests treatments for congenital progressive hearing loss.
Cell Rep. 18:68-81(2017)

PubMed=29179815; DOI=10.7554/eLife.21114; PMCID=PMC5705211
Okuno H., Renault-Mihara F., Ohta S., Fukuda K., Kurosawa K., Akamatsu W., Sanosaka T., Kohyama J., Hayashi K., Nakajima K., Takahashi T., Wysocka J.K., Kosaki K., Okano H.
CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.
eLife 6:e21114.1-e21114.26(2017)

PubMed=30127392; DOI=10.1038/s41591-018-0140-5
Fujimori K., Ishikawa M., Otomo A., Atsuta N., Nakamura R., Akiyama T., Hadano S., Aoki M., Saya H., Sobue G., Okano H.
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Nat. Med. 24:1579-1589(2018)

Cross-references
Cell line databases/resources SKIP; SKIP000514
Encyclopedic resources Wikidata; Q54993689
Entry history
Entry creation07-Nov-2014
Last entry update29-Jun-2023
Version number8