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Cellosaurus DF15R (CVCL_Y430)

[Text version]
Cell line name DF15R
Accession CVCL_Y430
Resource Identification Initiative To cite this cell line use: DF15R (RRID:CVCL_Y430)
Comments Selected for resistance to: ChEBI; CHEBI_72690; Pomalidomide (3-amino-thalidomide; CC-4047).
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y429 (DF15)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=22552008; DOI=10.1038/leu.2012.119; PMCID=PMC3496085
Antonia Lopez-Girona, Derek Mendy, Takumi Ito, Karen Miller, Anita K. Gandhi, Jian Kang, Satoki Karasawa, Gilles Carmel, Porshia Jackson, Mahan Abbasian, Afshin Mahmoudi ...Show all 20 authors... , Brian Cathers, Emily Rychak, Svetlana Gaidarova, R. Chen, Peter H. Schafer, Hiroshi Handa, Tom O. Daniel, Jilly Frances Evans, Rajesh Chopra; Show fewer authors
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide.
Leukemia 26:2326-2335(2012)

Cross-references
Encyclopedic resources Wikidata; Q54831024
Entry history
Entry creation07-Nov-2014
Last entry update14-Aug-2025
Version number8