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Cellosaurus L1210/DDP10 (CVCL_Y420)

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Cell line name L1210/DDP10
Synonyms L1210/DDP
Accession CVCL_Y420
Resource Identification Initiative To cite this cell line use: L1210/DDP10 (RRID:CVCL_Y420)
Comments Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Transformant: ChEBI; CHEBI_34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_Y418 (L1210/0)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=6541096
Alan Eastman, Sharon Illenye;
Murine leukemia L1210 cell lines with different patterns of resistance to platinum coordination complexes.
Cancer Treat. Rep. 68:1189-1190(1984)

PubMed=3828995
Victoria M. Richon, Nancy Schulte, Alan Eastman;
Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells.
Cancer Res. 47:2056-2061(1987)

PubMed=3167012; DOI=10.1021/bi00413a022
Alan Eastman, Nancy Schulte;
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
Biochemistry 27:4730-4734(1988)

PubMed=1986276; DOI=10.1016/0921-8777(91)90044-P
Margaretha M. Jennerwein, Alan Eastman, Abdul R. Khokhar;
The role of DNA repair in resistance of L1210 cells to isomeric 1,2-diaminocyclohexaneplatinum complexes and ultraviolet irradiation.
Mutat. Res. 254:89-96(1991)

PubMed=10200488; DOI=10.1038/sj.cdd.4400357
Evelyne Segal-Bendirdjian, Lionel Mannone, Alain Jacquemin-Sablon;
Alteration in p53 pathway and defect in apoptosis contribute independently to cisplatin-resistance.
Cell Death Differ. 5:390-400(1998)

Cross-references
Encyclopedic resources Wikidata; Q54900960
Entry history
Entry creation07-Nov-2014
Last entry update19-Dec-2024
Version number13