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Cellosaurus FL-74 (CVCL_Y090)

[Text version]
Cell line name FL-74
Synonyms FL74; FLA
Accession CVCL_Y090
Resource Identification Initiative To cite this cell line use: FL-74 (RRID:CVCL_Y090)
Comments Virology: Infected with feline leukemia virus (FeLV).
Doubling time: ~36 hours (PubMed=5818677).
Transformant: NCBI_TaxID; 11768; Feline leukemia virus.
Disease Feline lymphoma (NCIt: C132193)
Species of origin Felis catus (Cat) (Felis silvestris catus) (NCBI Taxonomy: 9685)
Hierarchy Children:
CVCL_6391 (FL-74-UCD-1)
Category Cancer cell line
Publications

PubMed=5818677; DOI=10.1038/222589b0
Theilen G.H., Kawakami T.G., Rush J.D., Munn R.J.
Replication of cat leukemia virus in cell suspension cultures.
Nature 222:589-590(1969)

PubMed=172437; DOI=10.1007/BF02832791
Olsen R.G., Milo G.E., Schaller J.P., Mathes L.E., Heding L.D., Yohn D.S.
Influence of culture conditions of growth of FL-74 cells and feline oncornavirus cell membrane associated antigen production.
In Vitro 12:37-43(1976)

PubMed=75945; DOI=10.1099/0022-1317-38-3-483
O'Brien S.J., Simonson J.M., Davis S.
Deposition of retrovirus associated antigens (p30 and gp70) on cell membranes of feline and murine leukaemia virus infected cells.
J. Gen. Virol. 38:483-496(1978)

PubMed=2822586; DOI=10.1002/ijc.2910400422
Miura T., Tsujimoto H., Fukasawa M., Kodama T., Shibuya M., Hasegawa A., Hayami M.
Structural abnormality and over-expression of the myc gene in feline leukemias.
Int. J. Cancer 40:564-569(1987)

PubMed=1313703; DOI=10.1292/jvms.54.173
Miyazawa T., Toyosaki T., Tomonaga K., Norimine J., Ohno K., Hasegawa A., Kai C., Mikami T.
Further characterization of a feline T-lymphoblastoid cell line (MYA-1 cells) highly sensitive for feline immunodeficiency virus.
J. Vet. Med. Sci. 54:173-175(1992)

PubMed=8138999; DOI=10.1128/JVI.68.4.2151-2160.1994
McDougall A.S., Terry A., Tzavaras T., Cheney C.M., Rojko J.L., Neil J.C.
Defective endogenous proviruses are expressed in feline lymphoid cells: evidence for a role in natural resistance to subgroup B feline leukemia viruses.
J. Virol. 68:2151-2160(1994)

Cross-references
Encyclopedic resources Wikidata; Q54834965
Entry history
Entry creation07-Nov-2014
Last entry update05-Oct-2023
Version number9