Cellosaurus cell line R3/1 (CVCL

Cellosaurus R3/1 (CVCL_XX96)

Cross-references
Cell line name	R3/1
Accession	CVCL_XX96
Resource Identification Initiative	To cite this cell line use: R3/1 (RRID:CVCL_XX96)
Comments	Characteristics: Alveolar epithelial type I-like. Doubling time: ~38 hours (Note=In RPMI 1640 + 10% FCS) (PubMed=15221420). Derived from site: In situ; Embryonic lung; UBERON=UBERON_0005597.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Wistar-Han; RS=RS_0005006.
Sex of cell	Male
Age at sampling	20FD
Category	Spontaneously immortalized cell line
Publications	PubMed=15221420; DOI=10.1007/s00418-004-0662-4 Roland Koslowski, Kathrin Barth, Antje Augstein, Thomas Tschernig, Gerhard Bargsten, Michaela Aufderheide, Michael Kasper; A new rat type I-like alveolar epithelial cell line R3/1: bleomycin effects on caveolin expression. Histochem. Cell Biol. 121:509-519(2004) PubMed=15856276; DOI=10.1007/s00418-004-0727-4 Kathrin Barth, Marcus Gentsch, Robert Blasche, A. Pfuller, Iryna Parshyna, Roland Koslowski, Gerold Barth, Michael Kasper; Distribution of caveolin-1 and connexin43 in normal and injured alveolar epithelial R3/1 cells. Histochem. Cell Biol. 123:239-247(2005) PubMed=19103287; DOI=10.1016/j.ejps.2008.11.010 Lenka Horalkova, Aneta Radziwon, Sibylle Endter, Rikke Sick Andersen, Roland Koslowski, Marek Witold Radomski, Pavel Dolezal, Carsten Ehrhardt; Characterisation of the R3/1 cell line as an alveolar epithelial cell model for drug disposition studies. Eur. J. Pharm. Sci. 36:444-450(2009)
Encyclopedic resources	Wikidata; Q98128783
Entry history
Entry creation	19-Dec-2019
Last entry update	10-Apr-2025
Version number	7