Cellosaurus cell line VU-SCC-RO (CVCL

Cellosaurus VU-SCC-RO (CVCL_XX22)

Cross-references
Cell line name	VU-SCC-RO
Accession	CVCL_XX22
Resource Identification Initiative	To cite this cell line use: VU-SCC-RO (RRID:CVCL_XX22)
Comments	Characteristics: Established from a xenograft. Doubling time: 43 +- 4 hours (PubMed=9139877). Omics: Genomics; Whole genome sequencing; Low read coverage.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=31541927).
Disease	Oropharyngeal squamous cell carcinoma (NCIt: C8181) Squamous cell carcinoma of the oropharynx (ORDO: Orphanet_500478)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	70Y
Category	Cancer cell line
Publications	PubMed=9139877; DOI=10.1002/(SICI)1097-0215(19970502)71:3<410::AID-IJC18>3.0.CO;2-J Marij J.P. Welters, Anne Marie Josephine Fichtinger-Schepman, Robert A. Baan, Mario A.J.A. Hermsen, Wim J.F. van der Vijgh, Jacqueline Cloos, Boudewijn J.M. Braakhuis; Relationship between the parameters cellular differentiation, doubling time and platinum accumulation and cisplatin sensitivity in a panel of head and neck cancer cell lines. Int. J. Cancer 71:410-415(1997) PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097 Anne M. van Harten, Jos B. Poell, Marijke Buijze, Arjen Brink, Susanne I. Wells, C. Rene Leemans, Rob M.F. Wolthuis, Ruud H. Brakenhoff; Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass. Oral Oncol. 98:53-61(2019)
Encyclopedic resources	Wikidata; Q98134596
Entry history
Entry creation	19-Dec-2019
Last entry update	10-Apr-2025
Version number	8