Cellosaurus cell line M409 [Human melanoma] (CVCL

Cellosaurus M409 [Human melanoma] (CVCL_XK04)

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Cell line name

M409 [Human melanoma]

Accession

CVCL_XK04

Resource Identification Initiative

To cite this cell line use: M409 [Human melanoma] (RRID:CVCL_XK04)

Comments

Omics: Transcriptomics; RNAseq.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=24735930).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_XK14 (M409-AR)

Sex of cell

Sex unspecified

Age at sampling

Age unspecified

Category

Cancer cell line

Publications

PubMed=24735930; DOI=10.1186/1476-4598-13-83; PMCID=PMC4021505
Amanda Lassen, Mohammad Atefi, Lidia Robert, Deborah Jean Lee Wong, Michael Cerniglia, Begonya Comin-Anduix, Antoni Ribas;
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
Mol. Cancer 13:83.1-83.14(2014)

PubMed=29229836; DOI=10.1073/pnas.1712064115; PMCID=PMC5748184
Ya-Peng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel Hin-Ying Ng, Jihoon W. Lee, Richard C. Koya ...Show all 15 authors... , Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, James Richard Heath; Show fewer authors
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Proc. Natl. Acad. Sci. U.S.A. 114:13679-13684(2017)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_XK04

Encyclopedic resources

Wikidata; Q95984289

Gene expression databases

ArrayExpress; E-MTAB-5493

Entry history

Entry creation

19-Dec-2019

Last entry update

10-Apr-2025

Version number