• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=22194965).
  
• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (PubMed=22194965; PubMed=29229836).
  

PubMed=22194965; DOI=10.1371/journal.pone.0028973; PMCID=PMC3237573
Mohammad Atefi, Erika Maria von Euw, Narsis Attar, Charles Ng, Connie Chu, De-Liang Guo, Ramin Nazarian, Bartosz Chmielowski, John A. Glaspy, Begonya Comin-Anduix, Paul Salomon Mischel ...Show all 13 authors... , Roger S. Lo, Antoni Ribas; Show fewer authors
Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.
PLoS ONE 6:e28973.1-e28973.12(2011)

PubMed=29229836; DOI=10.1073/pnas.1712064115; PMCID=PMC5748184
Ya-Peng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel Hin-Ying Ng, Jihoon W. Lee, Richard C. Koya ...Show all 15 authors... , Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, James Richard Heath; Show fewer authors
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Proc. Natl. Acad. Sci. U.S.A. 114:13679-13684(2017)