• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=22194965; PubMed=24735930).
  

PubMed=22194965; DOI=10.1371/journal.pone.0028973; PMCID=PMC3237573
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Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.
PLoS ONE 6:e28973.1-e28973.12(2011)

PubMed=24735930; DOI=10.1186/1476-4598-13-83; PMCID=PMC4021505
Amanda Lassen, Mohammad Atefi, Lidia Robert, Deborah Jean Lee Wong, Michael Cerniglia, Begonya Comin-Anduix, Antoni Ribas;
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
Mol. Cancer 13:83.1-83.14(2014)

PubMed=29229836; DOI=10.1073/pnas.1712064115; PMCID=PMC5748184
Ya-Peng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel Hin-Ying Ng, Jihoon W. Lee, Richard C. Koya ...Show all 15 authors... , Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, James Richard Heath; Show fewer authors
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
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