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Cellosaurus NCCIT_CDDP (CVCL_XI44)

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Cell line name NCCIT_CDDP
Accession CVCL_XI44
Resource Identification Initiative To cite this cell line use: NCCIT_CDDP (RRID:CVCL_XI44)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Sequence variations
  • Mutation; HGNC; HGNC:6844; MAP2K4; Simple; p.Lys309Asn (c.927G>C); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg173Pro (c.518G>C); ClinVar=VCV000185195; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val272Cysfs*73 (c.814delG); Zygosity=Homozygous (from parent cell line).
Disease Testicular embryonal carcinoma (NCIt: C6341)
Non-central nervous system-localized embryonal carcinoma (ORDO: Orphanet_289362)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1451 (NCC-IT)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=31500094; DOI=10.3390/cancers11091316; PMCID=PMC6769617
Violeta Bakardjieva-Mihaylova, Karolina Skvarova Kramarzova, Martina Slamova, Michael Svaton, Katerina Rejlova, Marketa Zaliova, Alena Dobiasova, Karel Fiser, Jan Stuchly, Marek Grega, Blanka Rosova ...Show all 18 authors... , Roman Zachoval, Petr Klezl, Vaclav Eis, Eva Kindlova, Tomas Buchler, Jan Trka, Ludmila Boublikova; Show fewer authors
Molecular basis of cisplatin resistance in testicular germ cell tumors.
Cancers (Basel) 11:1316.1-1316.18(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_XI44
Encyclopedic resources Wikidata; Q95992667
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number9