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Cellosaurus A549-ESM (CVCL_XI06)

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Cell line name A549-ESM
Synonyms A549-MSB
Accession CVCL_XI06
Resource Identification Initiative To cite this cell line use: A549-ESM (RRID:CVCL_XI06)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-1972.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3466; ESM1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

Patent=WO1999045028A1
Philippe Lassalle, Genevieve Marchandise, Gwenola Kervoaze, Andre-Bernard Tonnel;
Monoclonal antibodies ESM-1 protein specific, and use of said antibodies for detecting ESM-1 protein.
Patent number WO1999045028A1, 10-Sep-1999

Cross-references
Cell line databases/resources cancercelllines; CVCL_XI06
Encyclopedic resources Wikidata; Q93311939
Entry history
Entry creation19-Dec-2019
Last entry update14-Aug-2025
Version number11