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Cellosaurus 44As3 (CVCL_XG62)

[Text version]
Cell line name 44As3
Accession CVCL_XG62
Resource Identification Initiative To cite this cell line use: 44As3 (RRID:CVCL_XG62)
Comments Population: Japanese.
Characteristics: Highly metastatic. Strong capability of inducing the formation of ascites.
Characteristics: Parent cell line was injected subcutaneously into BALB/c nude mice. Cells from metastatic ascitic tumor cells were harvested and re-injected into mice. This process was carried out 12 times.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A388 (HSC-44PE)
Children:
CVCL_C7UQ (44As3Luc)
Sex of cell Female
Age at sampling 28Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1888

Markers:
AmelogeninX
CSF1PO11,12
D5S81810
D7S82011
D13S3178
D16S53913
TH018,9
TPOX8
vWA17

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Publications

PubMed=15958054; DOI=10.1111/j.1349-7006.2005.00054.x; PMCID=PMC11158165
Kazuyoshi Yanagihara, Misato Takigahira, Hiromi Tanaka, Teruo Komatsu, Hisao Fukumoto, Fumiaki Koizumi, Kazuto Nishio, Takahiro Ochiya, Yoshinori Ino, Setsuo Hirohashi;
Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer.
Cancer Sci. 96:323-332(2005)

PubMed=19010905; DOI=10.1158/0008-5472.CAN-08-2822
Takako Eguchi Nakajima, Kazuyoshi Yanagihara, Misato Takigahira, Masahiro Yasunaga, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Keichiro Mihara, Takahiro Ochiya, Yasuhiro Matsumura;
Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.
Cancer Res. 68:9318-9322(2008)

PubMed=26934957; DOI=10.1038/srep22371; PMCID=PMC4776110
Junji Kurashige, Takanori Hasegawa, Atsushi Niida, Keishi Sugimachi, Nian-Tao Deng, Kosuke Mima, Ryutaro Uchi, Genta Sawada, Yusuke Takahashi, Hidetoshi Eguchi, Masashi Inomata ...Show all 22 authors... , Seigo Kitano, Takeo Fukagawa, Mitsuru Sasako, Hiroki Sasaki, Shin Sasaki, Masaki Mori, Kazuyoshi Yanagihara, Hideo Baba, Satoru Miyano, Patrick Tan, Koshi Mimori; Show fewer authors
Integrated molecular profiling of human gastric cancer identifies DDR2 as a potential regulator of peritoneal dissemination.
Sci. Rep. 6:22371-22371(2016)

Cross-references
Cell line collections (Providers) JCRB; JCRB1888
Encyclopedic resources Wikidata; Q93307015
Entry history
Entry creation06-Sep-2019
Last entry update02-May-2024
Version number6