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Cellosaurus BW125.1C (CVCL_XG61)

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Cell line name BW125.1C
Accession CVCL_XG61
Resource Identification Initiative To cite this cell line use: BW125.1C (RRID:CVCL_XG61)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1674; CD3E (Note=With p.Met1_Ser152del; IL2RA-CD3E chimeric receptor).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6008; IL2RA (Note=With p.Thr260_Ile272del; IL2RA-CD3E chimeric receptor).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:99919; Vcp (Note=With a C-terminal human MYC epitope).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: AKR/J.
Hierarchy Parent: CVCL_3896 (BW5147)
Category Cancer cell line
Publications

PubMed=1382975; DOI=10.1002/j.1460-2075.1992.tb05436.x; PMCID=PMC556811
Mark Egerton, O.R. Ashe, Douglas Chen, Brian Jay Druker, Wilson H. Burgess, Lawrence E. Samelson;
VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation.
EMBO J. 11:3533-3540(1992)

PubMed=8157674; DOI=10.1016/S0021-9258(19)78142-3
Mark Egerton, Lawrence E. Samelson;
Biochemical characterization of valosin-containing protein, a protein tyrosine kinase substrate in hematopoietic cells.
J. Biol. Chem. 269:11435-11441(1994)

Cross-references
Encyclopedic resources Wikidata; Q93433387
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number9