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Cellosaurus PH2MT (CVCL_XG27)

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Cell line name PH2MT
Accession CVCL_XG27
Resource Identification Initiative To cite this cell line use: PH2MT (RRID:CVCL_XG27)
Comments Characteristics: Derived from a tumor formed in athymic mice by injection of the parent cell line.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: v-Myc.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XG25 (MSU-1.1-T24 2)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=11888918
Pamela A. Havre, Sandra O'Reilly, J. Justin McCormick, Douglas E. Brash;
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.
Cancer Res. 62:1443-1449(2002)

PubMed=15705902
Zhen-Jun Lou, Sandra O'Reilly, Hong-Yan Liang, Veronica M. Maher, Stuart D. Sleight, J. Justin McCormick;
Down-regulation of overexpressed Sp1 protein in human fibrosarcoma cell lines inhibits tumor formation.
Cancer Res. 65:1007-1017(2005)

Cross-references
Encyclopedic resources Wikidata; Q98128570
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number9