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Cellosaurus STA5 (CVCL_XF78)

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Cell line name STA5
Synonyms STA 5
Accession CVCL_XF78
Resource Identification Initiative To cite this cell line use: STA5 (RRID:CVCL_XF78)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0548 (SaOS-2)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=7588596; DOI=10.1002/j.1460-2075.1995.tb00148.x; PMCID=PMC394563
Christoph Englert, Xian-Yu Hou, Shyamala Maheswaran, Patrick Bennett, Chidi Ngwu, Gian G. Re, Abbott Julian Garvin, Marsha Rich Rosner, Daniel Arie Haber;
WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis.
EMBO J. 14:4662-4675(1995)

Cross-references
Encyclopedic resources Wikidata; Q98132847
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number11