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Cellosaurus A549-Luc2-tdT-2 (CVCL_XE69)

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Cell line name A549-Luc2-tdT-2
Accession CVCL_XE69
Resource Identification Initiative To cite this cell line use: A549-Luc2-tdT-2 (RRID:CVCL_XE69)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000632

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133824
D3S135816
D5S81811
D6S104311,13
D7S8208,11
D8S117913,14
D12S39118
D13S31711
D16S53911,12
D18S5114,17
D19S43313
D21S1129
FGA23
Penta E7,11
TH018,9.3
TPOX8,11
vWA14

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Cross-references
Cell line databases/resources cancercelllines; CVCL_XE69
CCRID; 1101HUM-PUMC000632
Encyclopedic resources Wikidata; Q93311984
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number14