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Cellosaurus WAe001-A-26 (CVCL_XD77)

[Text version]
Cell line name WAe001-A-26
Synonyms H1_MECP2_M2; M2; MAPe002-A-26
Accession CVCL_XD77
Resource Identification Initiative To cite this cell line use: WAe001-A-26 (RRID:CVCL_XD77)
Comments From: Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research; Singapore; Singapore.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:6990; MECP2; Simple_edited; p.Thr160_Lys233del; Zygosity=Hemizygous; Note=By CRISPR/Cas9 (PubMed=31450191).
Disease Rett syndrome (NCIt: C75488)
Rett syndrome (ORDO: Orphanet_778)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=31450191; DOI=10.1016/j.scr.2019.101533
Rui-Zhu Zeng, Harwin Sidik, Kim S. Robinson, Franklin L. Zhong, Bruno Reversade, Mahmoud A. Pouladi;
Generation of four H1 hESC sublines carrying a hemizygous knock-out/mutant MECP2.
Stem Cell Res. 40:101533-101533(2019)

Cross-references
Cell line databases/resources hPSCreg; WAe001-A-26
Encyclopedic resources Wikidata; Q98134697
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number9