Cellosaurus logo
expasy logo

Cellosaurus SK-OV-3-Cas9-560 (CVCL_XB82)

[Text][XML][JSON]
Cell line name SK-OV-3-Cas9-560
Accession CVCL_XB82
Resource Identification Initiative To cite this cell line use: SK-OV-3-Cas9-560 (RRID:CVCL_XB82)
Comments Population: Caucasian.
Characteristics: Transduced with a Cas9-FLAG-Neo construct.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (Note=With a C-terminal FLAG tag).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000560

Markers:
AmelogeninX
CSF1PO11
D2S133818,23
D3S135814
D5S81811
D6S104312
D7S82013,14
D8S117914,15
D12S39122
D13S3178,11
D16S53912
D18S5116,17
D19S43314,14.2
D21S1130,31.2
FGA24,25
Penta E5,13
TH019,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_XB82
CCRID; 1101HUM-PUMC000560
Encyclopedic resources Wikidata; Q98132664
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number14