Cellosaurus cell line (CVCL

Entry history
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr. Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:903; AXIN1; Simple; p.Arg712Ter (c.2134C>T); Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Arg (c.416A>G); ClinVar=VCV001500748; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
Disease	Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin	Felis catus (Cat) (Felis silvestris catus) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0454 (SNU-449)
Sex of cell	Male
Age at sampling	52Y
Category	Cancer cell line
Entry creation	25-Jun-2026
Last entry update	25-Jun-2026
Version number	1