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Cellosaurus 4T1-Par3 (CVCL_XB02)

[Text version]
Cell line name 4T1-Par3
Accession CVCL_XB02
Resource Identification Initiative To cite this cell line use: 4T1-Par3 (RRID:CVCL_XB02)
Comments Part of: Brain metastasis cell lines panel.
Characteristics: Brain parenchymal space metastatic derivative of parental cell line. Established after 3 passages in BALC/cAn mice from internal carotid artery injection.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cfC3H.
Hierarchy Parent: CVCL_XG69 (4T1/GFP/FlucII)
Sex of cell Female
Category Cancer cell line
Web pages https://apps.cnio.es/app/BrainMetastasis/CellLines

PubMed=27203741; DOI=10.18632/oncotarget.9445
Rippaus N., Taggart D., Williams J., Andreou T., Wurdak H., Wronski K., Lorger M.
Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases.
Oncotarget 7:41473-41487(2016)

Encyclopedic resources Wikidata; Q93307547
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number6