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Cellosaurus MEL-1 INSGFP/w (CVCL_XA16)

[Text version]
Cell line name MEL-1 INSGFP/w
Synonyms MEL1 INSGFP/w; MEL1 INS(GFP/w); Mel1-INS-GFP
Accession CVCL_XA16
Resource Identification Initiative To cite this cell line use: MEL-1 INSGFP/w (RRID:CVCL_XA16)
Comments Characteristics: Using homologous recombination an EGFP reporter gene was introduced in the INS locus (PubMed=22120512).
Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B863 (SCSe001-A)
Children:
CVCL_XA17 (MEL-1 INSGFP/w NEUROD1(-/-))CVCL_A4WX (SCSe001-A-3)CVCL_C1W6 (SCSe001-A-4)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=22120512; DOI=10.1007/s00125-011-2379-y; PMCID=PMC3268987
Suzanne J. Micallef, X. Li, Jacqueline V. Schiesser, Claire E. Hirst, Qing C. Yu, S.M. Lim, Maria Cristina Nostro, David A. Elliott, Farida Sarangi, Leonard Charles Harrison, Gordon M. Keller ...Show all 13 authors... , Andrew George Elefanty, Edouard G. Stanley; Show fewer authors
INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.
Diabetologia 55:694-706(2012)

Cross-references
Encyclopedic resources Wikidata; Q95988515
Entry history
Entry creation06-Sep-2019
Last entry update10-Sep-2024
Version number6