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Cellosaurus HES-3 INSGFP/w (CVCL_XA15)

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Cell line name HES-3 INSGFP/w
Synonyms HES3 INS(GFP/w); HES3 INSGFP/w; INSULIN(GFP/w) HES3
Accession CVCL_XA15
Resource Identification Initiative To cite this cell line use: HES-3 INSGFP/w (RRID:CVCL_XA15)
Comments Characteristics: Using homologous recombination an EGFP reporter gene was introduced in one allele of the INS locus (PubMed=22120512).
Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7158 (HES-3)
Children:
CVCL_C0CN (ESIBIe003-A-10)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=22120512; DOI=10.1007/s00125-011-2379-y; PMCID=PMC3268987
Suzanne J. Micallef, Xue-Ling Li, Jacqueline V. Schiesser, Claire E. Hirst, Qing C. Yu, Sue Mei Lim, Maria Cristina Nostro, David A. Elliott, Farida Sarangi, Leonard Charles Harrison, Gordon M. Keller ...Show all 13 authors... , Andrew George Elefanty, Edouard G. Stanley; Show fewer authors
INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.
Diabetologia 55:694-706(2012)

Cross-references
Encyclopedic resources Wikidata; Q94104651
Entry history
Entry creation06-Sep-2019
Last entry update10-Sep-2024
Version number7