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Cellosaurus HUOA (CVCL_X935)

[Text version]
Cell line name HUOA
Accession CVCL_X935
Resource Identification Initiative To cite this cell line use: HUOA (RRID:CVCL_X935)
Comments Population: Japanese.
Doubling time: 78 hours (Note=At 40th passage), 77 hours (Note=At 100th passage) (PubMed=3598277); 80 hours (PubMed=3593088).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=2429643; DOI=10.1111/j.1447-0756.1986.tb00192.x
Isamu Ishiwata, Chieko Ishiwata, Shiro Nozawa, Hiroshi Ishikawa;
CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.
Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986)

PubMed=3593088; DOI=10.1111/j.1447-0756.1987.tb00014.x
Isamu Ishiwata, Chieko Ishiwata, Shiro Nozawa, Hiroshi Ishikawa;
Cytological properties of human ovarian carcinoma cell lines.
Asia Oceania J. Obstet. Gynaecol. 13:79-86(1987)

PubMed=3598277
Isamu Ishiwata, Chieko Ishiwata, Noburu Kobayashi, Hiroshi Ishikawa;
Characterization of newly established cell line HUOA from a human ovarian serous cystadenocarcinoma.
Nihon Sanka Fujinka Gakkai Zasshi 39:831-836(1987)

PubMed=2448191; DOI=10.1016/0090-8258(88)90151-5
Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Isao Ono, Takenori Nakaguchi, Hiroshi Ishikawa;
Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.
Gynecol. Oncol. 29:87-93(1988)

PubMed=9573483
Isamu Ishiwata, Yuko Tokieda, Chieko Ishiwata, Natsumi Okane, Megumi Iguchi, Kahei Sato, Hiroshi Ishikawa;
Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.
Hum. Cell 10:237-246(1997)

PubMed=10457904
Isamu Ishiwata, Tadashi Sudo, Kazushige Kiguchi, Hiroshi Ishikawa;
Tumor angiogenesis factors produced by cancer cells.
Hum. Cell 12:37-46(1999)

PubMed=11330945; DOI=10.1006/gyno.2001.6132
Takafumi Watanabe, Issei Imoto, Yoshinori Kosugi, Isamu Ishiwata, Satoshi Inoue, Masaomi Takayama, Akira Sato, Johji Inazawa;
A novel amplification at 17q21-23 in ovarian cancer cell lines detected by comparative genomic hybridization.
Gynecol. Oncol. 81:172-177(2001)

PubMed=12417041; DOI=10.1111/j.1349-7006.2002.tb01213.x; PMCID=PMC5926887
Takafumi Watanabe, Issei Imoto, Tomoyuki Katahira, Akira Hirasawa, Isamu Ishiwata, Mitsuru Emi, Masaomi Takayama, Akira Sato, Johji Inazawa;
Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.
Jpn. J. Cancer Res. 93:1114-1122(2002)

PubMed=17671176; DOI=10.1158/0008-5472.CAN-06-4567
Ryoko Kikuchi, Hitoshi Tsuda, Yae Kanai, Takahiro Kasamatsu, Kazuo Sengoku, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
Cancer Res. 67:7095-7105(2007)

Cross-references
Cell line databases/resources CGH-DB; 341-2
CGH-DB; 9349-4
Encyclopedic resources Wikidata; Q54896892
Polymorphism and mutation databases Cosmic; 877484
Cosmic; 1152564
Entry history
Entry creation05-Sep-2014
Last entry update10-Apr-2025
Version number10